The 2021–22 Thai League Cup is the 12th season in the second era of a Thailand's knockout football competition.

It was sponsored by Toyota Motor Thailand, and known as the Hilux Revo League Cup (Thai: ไฮลักซ์ รีโว่ ลีกคัพ) for sponsorship purposes, Hilux Revo is a truck model of Toyota.

75 clubs were accepted into the tournament, and it began with the first qualification round on 13 October 2021 and concluded with the final on 29 May 2022.

The tournament has been readmitted back into Thai football after a 10-year absence.

This is the first edition of the competition and the qualifying round will be played in regions featuring clubs from the Thai League 3.

The qualification play-off round would be featured 20 clubs that were the winners of the second qualification round[3] and the new entries that were 12 clubs from the 2021–22 Thai League 2.