The 2021–22 Toledo Rockets men's basketball team represented the University of Toledo during the 2021–22 NCAA Division I men's basketball season.

The Rockets, led by 12th-year head coach Tod Kowalczyk, played their home games at Savage Arena, as members of the Mid-American Conference.

They defeated Central Michigan in the quarterfinals of the MAC tournament before losing in the semifinals to Akron.

1 seed who failed to win their conference tournament, they received an automatic bid to the National Invitation Tournament where they lost in the first round to Dayton.

They received an at-large bid to the National Invitation Tournament where they lost to Richmond in the first round.