The 2021–22 Towson Tigers men's basketball team represented Towson University during the 2021–22 NCAA Division I men's basketball season.

The Tigers, led by 11th-year head coach Pat Skerry, played their home games at the SECU Arena in Towson, Maryland as members of the Colonial Athletic Association.

The Tigers finished the 2021–22 season 25–9, 15–3 in CAA play to finish as CAA regular season co-champions, alongside UNC Wilmington.

As the top seed in the CAA tournament, they defeated Northeastern in the quarterfinals, before being upset by No.

As a regular season champion, who failed to win their league tournament, the Tigers earned an automatic bid to the NIT, where they lost in the first round to Wake Forest.