The 2021–22 UCF Knights men's basketball team represented the University of Central Florida during the 2021–22 NCAA Division I men's basketball season.

The Knights competed as members of the American Athletic Conference.

The Knights, in the program's 53rd season of basketball, were led by sixth-year head coach Johnny Dawkins and played their home games at the Addition Financial Arena on the university's main campus in Orlando, Florida.

They defeated South Florida in the First Round of the AAC Tournament before losing in the quarterfinals to Memphis.

They defeated East Carolina in the first round of the AAC tournament before losing to Memphis in the quarterfinals.