The 2021–22 UEFA Europa Conference League group stage began on 14 September 2021 and ended on 9 December 2021.
[1] A total of 32 teams competed in the group stage to decide 16 of the 24 places in the knockout phase of the 2021–22 UEFA Europa Conference League.
[2] Alashkert, Bodø/Glimt, Flora, Kairat, Lincoln Red Imps, Mura, Randers and Union Berlin made their debut appearances in a UEFA competition group stage.
Alashkert, Flora and Lincoln Red Imps were the first teams from Armenia, Estonia and Gibraltar, respectively, to play in a UEFA competition group stage.
If two or more teams were tied on points, the following tiebreaking criteria were applied, in the order given, to determine the rankings (see Article 16 Equality of points – group stage, Regulations of the UEFA Europa Conference League):[2] Due to the abolition of the away goals rule, head-to-head away goals were no longer applied as a tiebreaker starting from this season.