The 2021–22 UNC Wilmington Seahawks men's basketball team represented the University of North Carolina Wilmington during the 2021–22 NCAA Division I men's basketball season.

The Seahawks are led by second-year head coach Takayo Siddle.

They played their home games at Trask Coliseum as part of the Colonial Athletic Association.

The Seahawks defeated Elon and Charleston in the CAA tournament before losing to Delaware in the championship game.

They defeated VMI, Drake, Northern Colorado, and Middle Tennessee to win the CBI championship.