The 2021–22 Ukrainian Cup was the 31st annual season of Ukraine's football knockout competition.
All competition rounds consist of a single game with a home field advantage granted to a team from lower league.
Qualification for the competition was granted to all professional clubs and two better of the 2020–21 Ukrainian Amateur Cup.
At an extraordinary general meeting on 26 April 2022, the competition was abandoned due to the Russian invasion of Ukraine.
The competition's top ten goalscorers including preliminary rounds.