The 2021–22 VMI Keydets basketball team represented the Virginia Military Institute in the 2021–22 NCAA Division I men's basketball season.

The Keydets, led by seventh-year head coach Dan Earl, played their home games in Cameron Hall in Lexington, Virginia as members of the Southern Conference.

5 seed in the SoCon tournament, they lost to Wofford in the quarterfinals.

In a season limited due to the ongoing COVID-19 pandemic, the Keydets finished the 2020–21 season 13–12, 7–7 in SoCon play to finish in sixth place.

They upset Furman in overtime in the quarterfinals of the SoCon tournament,[2] before falling to Mercer in the semifinals.