The Premier Division was increased from 20 clubs to 21, after Lymington Town were promoted to the Southern League, and Fleet Town and Tadley Calleva were transferred to the Combined Counties League.
Four new teams joined the division: Infinity withdrew from the league on 6 February 2022 after their groundshare agreement with Hythe & Dibden was terminated by Hythe.
This followed an incident in which an Infinity player was sent off during a match for using racist language.
Subsequent attempts to find another ground at which Infinity could play were unsuccessful.
[6] Infinity's playing record was later expunged from the league table.