Women season was the club's 31st season in existence and their fourth in the FA Women's Super League, the highest level of the football pyramid.

On 20 May 2021, Jack Sullivan stepped down as managing director after four years in the job.

[1] Following the final game of the season, it was announced Olli Harder had informed the club of his resignation to pursue new opportunities.

Assistant manager Paul Konchesky was immediately announced as his successor on a two-year contract.

[2] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.