The 2021–22 West Indies Championship was the 55th edition of the Regional Four Day Competition, the domestic first-class cricket competition for the countries of the Cricket West Indies (CWI), which started on 9 February 2022.

[2] The series was played for the Headley–Weekes Trophy, named after George Headley and Sir Everton Weekes.

The final two rounds of that tournament were cancelled due to the COVID-19 pandemic.

[8][9] The first two rounds of fixtures took place in February 2022, followed by a break for the Test match series between the West Indies and England, with CWI announcing the fixtures for the final three rounds of matches in late March 2022.

[10] On the last day of the fifth and final round of matches, Barbados won the tournament to retain their title.