The 2021–22 Wisła Kraków season was the 82nd season in the Ekstraklasa and the 68th season in the Polish Cup.

Last updated: 21 May 2022.

Source: 90minut Last updated: 21 May 2022Source: Competitive matchesOnly competitive matches = Number of bookings; = Number of sending offs after a second yellow card; = Number of sending offs by a direct red card.