The schedule of the competition was as follows (all draws were held at the EHF headquarters in Vienna, Austria).
In each group, teams played against each other in a double round-robin format, with home and away matches.
If no ranking can be determined, a decision shall be obtained by EHF through drawing of lots.
During the group stage, only criteria 4–5 apply to determine the provisional ranking of teams.
The final four was held at the Vibocold Arena in Viborg, Denmark on 14 and 15 May 2022.