Therefore Surbiton were the defending champions, having won the league during the 2019–20 season.
The season started on 18 September 2021, with the Premier Division using a new system of two phases.
[3] Beeston finished fifth in the league standings but won the 2022 England Hockey Women's Championship Cup.
[4] Beeston Steph Tirrell (gk), Julie Whiting, Ella Cusack, Alice Huddlestone, Lauren Burrell (capt), Hannah Grieve, Maddie Pendle, Charlotte Summers, Sophie Robinson, Lucy Millington, Paige Gillott; reps: Cerys Miller, Ruby Apoola, Beatrice Bell, Madeleine Newitt, Nadia Benallal; coach: James Sordillo; manager: Zoe Hainsworth.
Buckingham Nicole Marks (gk), Megan Lewis-Williams, Emma O'Nien, Lottie Porter (capt), Maddy Newlyn, Lauren Thomas, Kirsty Freshwater, Natasha James, Tilly Crampsie, Rebecca van Arrowsmith, Olivia Strickland; reps: Georgina Black, Alex Naughalty, Cassidy Jorritsma, Deborah James; manager: Kate Porter.