[2] Tasmania won the competition, their first WNCL title, beating South Australia in the final.

Cricket Australia announced the original schedule on 21 July 2021, with the season set to begin on 23 September 2021 and the final to take place on 6 March 2022.

[3] However, on 8 September 2021, it was announced that the season start would be delayed until 16 December 2021 following the completion of WBBL/07 due to lockdowns in Sydney and Melbourne and subsequent border restrictions, with a full revised schedule to be released "in due course".

[4][5] The revised fixtures were released on 18 November 2021, with the season set to start with a match between Victoria and ACT Meteors on 16 December 2021 and the final date unchanged.

[6] However, on 10 December 2021, it was announced that Western Australia border closures and the need for Meteors players to self-isolate would mean further schedule changes, including the postponement of the original season opener between Victoria and the Meteors until later in the season.