The domestic season began on the weekend of 10 July 2021 with the first Scottish League Cup group stage matches.

Most regional leagues began on the weekend of 17 July and the opening round of matches in the 2021–22 Scottish Professional Football League were played on 31 July.

[30] UEFA Europa Conference League UEFA Europa Conference League Hibernian qualified for the 2021–22 UEFA Europa Conference League[43] and entered in the second qualifying round.

[37] UEFA Europa Conference League Aberdeen qualified for the 2021–22 UEFA Europa Conference League and entered in the second qualifying round.

Glasgow City and Celtic qualified for the Women's Champions League.