The 38-game season commenced on 27 August 2021 and concluded on 30 April 2022, with the play-offs taking place during the first two weeks in May 2022.
A 2–0 win over Coleraine meant that the Blues pipped runners-up Cliftonville to the title by a single point.
It was also the narrowest title-winning margin since the 2008–09 season, when Glentoran won the title by a single point ahead of Linfield.
The second and third tiers had not been granted 'elite' sporting status by the IFA which was required in order to continue playing matches during the COVID-19 pandemic lockdown, with lower division clubs not having played any league fixtures since the 2019–20 season had initially been suspended in March 2020.
[4] Dungannon Swifts finished bottom of the table the previous season, but were reprieved from relegation.