Group B of the 2021 Africa Cup of Nations qualification tournament was one of the twelve groups that decided the teams which qualified for the 2021 Africa Cup of Nations finals tournament.
The group consisted of four teams: Burkina Faso, Uganda, Malawi, and South Sudan (winners of the preliminary round).
[1] The teams played against each other in home-and-away round-robin format, originally scheduled between November 2019 and September 2020.
[2][3] Due to the COVID-19 pandemic, all matches of matchdays 3 and 4 scheduled for March 2020 were postponed until further notice.
[8] Burkina Faso and Malawi, the group winners and runners-up respectively, qualified for the 2021 Africa Cup of Nations.