The first tour was in July, 2021, and was composed of three matches in Romania and Wales, as preparation for the 2021 Rugby Championship.

[3] The second tour started in November, 2021, after the Pumas concluded their participation in the Rugby Championship with no successful results (having lost the six matches played).

[4][5] The squad visited France, Italy, and Ireland to play a series of test matches in those countries.

[8] Players that were called up for both tours, were: Matías Alemanno, Gonzalo Bertranou, Emiliano Boffelli, Facundo Bosch, Rodrigo Bruni, Santiago Carreras, Santiago Chocobares, Santiago Cordero, Tomás Cubelli, Jerónimo De la Fuente, Bautista Delguy, Felipe Ezcurra, Facundo Gigena, Francisco Gorrisen, Francisco Gómez Kodela, Juan Imhoff, Facundo Isa, Marcos Kremer, Tomás Lavanini, Tomás Lezana, Pablo Matera, Santiago Medrano, Domingo Miotti, Julián Montoya (captain), Matías Moroni, Matías Orlando, Guido Petti, Enrique Pieretto, Nicolás Sánchez, Santiago Socino, Nahuel Tetaz Chaparro, and Federico Wgrzyn.

Players selected that were not part of the first tour were Eduardo Bello, Mateo Carreras, Lucio Cinti, Facundo Cordero, Thomas Gallo, Gonzalo García, Juan Martín González, Santiago Grondona, Juan Cruz Mallía, Lucas Mensa, and Ignacio Ruiz.