The 2021 Campeonato Brasileiro Série B was a football competition held in Brazil, equivalent to the second division.
[1] Twenty teams competed in the tournament, twelve returning from the 2020 season, four promoted from the 2020 Campeonato Brasileiro Série C (Brusque, Londrina, Remo and Vila Nova),[2] and four relegated from the 2020 Campeonato Brasileiro Série A (Botafogo, Coritiba, Goiás and Vasco da Gama).
[3] Brusque were deducted three points after they were punished by Superior Tribunal de Justiça Desportiva (STJD) for racial abuse aimed toward Londrina's player Celsinho during the match Brusque v Londrina, played on 28 August (21st round).
[4] On 18 November 2021, STJD overturned its decision and the three points were returned to Brusque.
[5] The top four teams were promoted to the 2022 Campeonato Brasileiro Série A. Botafogo and Coritiba became the first two clubs to be promoted on 15 November 2021 after a 2–1 win against Operário Ferroviário and a 1–0 Brusque win against CRB, respectively.