It was held on 28 February 2021 as a category 1.Pro race on the 2021 UCI Europe Tour and the 2021 UCI ProSeries.

The race was 197 km (122 mi) long, starting and finishing in Kuurne, and featured several cobbled sections and climbs.

[1] The race formed the latter half of the opening weekend of the Belgian road cycling season with UCI WorldTour race Omloop Het Nieuwsblad held the previous day.

[2] Seventeen of the nineteen UCI WorldTeams were joined by eight UCI ProTeams to make up the twenty-five teams that participated in the race.

All but one team entered seven riders for a total of 174 riders, many of whom also contested the previous day's Omloop Het Nieuwsblad; Trek–Segafredo was the exception with six riders, as Charlie Quarterman sustained injuries from a crash during that race.