This was the seventh straight season without making the postseason (the third longest drought in team history) and the sixth in a row with a losing record (the worst span since the 1971–77 seasons).

The season was also the first for play-by-play commentators Matt Vasgersian and Daron Sutton who assumed a split role after the departure of Victor Rojas.

The Angels parted ways with Sutton midway through the season.

Source: MLB Standings Grid – 2021 Updated with the results of all games through October 3, 2021.

Note: POS = Position; G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; BB = Walks; SB = Stolen bases; AVG = Batting average; OBP = On-base percentage plus slugging; SLG = Slugging percentage; OPS = On-base percentage plus slugging (Updated stats through October 3, 2021) Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed, SO = Strikeouts (Updated stats through October 3, 2021) Infielders Outfielders Coaches All coaches and rosters can be found on each team's website.