The Wolverines, led by head coach Erik Bakich in his ninth season, are a member of the Big Ten Conference and played their home games at Wilpon Baseball Complex in Ann Arbor, Michigan.

[3] On November 6, 2020, former Michigan pitching coach Chris Fetter was named pitching coach for the Detroit Tigers of Major League Baseball (MLB).

[6][7] Redshirt sophomore Steven Hajjar was named to the Preseason All-America Third Team.

[8] On March 4, the Big Ten Coaches voted Michigan as the preseason favorite to win the conference.

The following Wolverines were selected in the 2021 Major League Baseball draft:[13][14]