The 2021 Missouri Tigers football team represented the University of Missouri in the 2021 NCAA Division I FBS football season.

The Tigers played their home games at Faurot Field in Columbia, Missouri, and competed in the Eastern Division of the Southeastern Conference (SEC).

They were led by second-year head coach Eliah Drinkwitz.

[1] at Faurot Field, Columbia, MO at Faurot Field, Columbia, Missouri Second quarter Third quarter Fourth quarter Statistics Statistics at Sanford Stadium • Athens, Georgia at Faurot Field • Columbia, Missouri

at Donald W. Reynolds Razorback Stadium • Fayetteville, Arkansas at Amon G. Carter Stadium, Fort Worth, TX