4 Ohio State opened the season at Huntington Bank Stadium, where they faced the Minnesota Golden Gophers.

Ohio State took an early lead on 71-yard touchdown run by Miyan Williams and a 35-yard field goal.

On the ensuing possession, Haskell Garrett recovered a strip sack and returned the fumble 32 yards for a touchdown and pushing the Buckeye lead to 31–21.

Following a Minnesota field goal, Stroud hit TreVeyon Henderson on a 70-yard pass and run to extend OSU's lead to 14.

3 Ohio State Buckeyes 35–28 in a rematch of the 2015 College Football Playoff National Championship.