The 2021 Oregon Ducks football team represented the University of Oregon during the 2021 NCAA Division I FBS football season.

The team was led by fourth-year head coach Mario Cristobal, who left the program to take the head coaching job at Miami in early December.

[1] The Ducks played their home games at Autzen Stadium in Eugene, Oregon, and competed as members of the North Division of the Pac-12 Conference.

[2][3][4][5] Roster [6] at Autzen Stadium • Eugene, OR First win against Ohio State (0–9 previously).

at Ohio Stadium • Columbus, OH at Autzen Stadium • Eugene, OR at Autzen Stadium • Eugene, OR at Stanford Stadium • Stanford, CA at Autzen Stadium • Eugene, OR at Rose Bowl • Pasadena, CA at Autzen Stadium • Eugene, OR at Husky Stadium • Seattle, WA at Autzen Stadium • Eugene, OR at Rice-Eccles Stadium • Salt Lake City, UT at Autzen Stadium • Eugene, OR at Allegiant Stadium • Las Vegas, NV at Alamodome • San Antonio, Texas