The Pitt baseball team competes in the Atlantic Coast Conference and plays their home games at Charles L. Cost Field in the Petersen Sports Complex.

Although early records are sparse and incomplete, baseball at the university continued to be played against nearby college teams, although sometimes with irregular schedules, throughout the end of the 19th century, as well as at the intramural level.

[4] However, according to the student yearbook, in the early 20th century interest in college baseball at Pitt waned due to a lack of a proper field, strictness of eligibility rules, irregularity of schedules, and the rise of football as the dominant school sport.

[5] The program was reestablished in 1939 under coach Ralph Mitterling who led the team for 16 seasons and guided players such as future Major League pitcher Russ Kemmerer.

[8] Lewis coached All-Americans George Schoeppner and Fred Mazurek, future long-time Major League professionals Doc Medich and Ken Macha, as well as other notable athletes such as Mike Ditka and Joe Walton.

[7][9] Mark Jackson took over for Bobby Lewis in 1991 and quickly turned the Panthers into a contender in the Big East Conference, in which Pitt had begun competing in 1985.

[13] Since 2000, Jordano's teams have produced nine All-Americans, 20 All-region selections, six 30-win seasons, and six Big East Baseball Tournament appearances.

Jordano earned the Big East Coach of the Year award in 2004 following a 38–18 season in which Pitt finished second in the conference standings.

[30][46][47][48] Other Pitt players that had Major League careers include Steve Swetonic, Robert Malloy, Russ Kemmerer, and Jason Rakers.