The 2021 Players Championship (officially the 2021 Cazoo Players Championship) was a professional ranking snooker tournament, that took place from 22 to 28 February 2021 at the Marshall Arena in Milton Keynes.

Judd Trump was the defending champion, having defeated Yan Bingtao 10–4 in the 2020 final.

The final was contested between John Higgins and Ronnie O'Sullivan, their first meeting in a ranking final since the 2005 Grand Prix, with Higgins winning 10–3.

This was O'Sullivan's 57th ranking final, equalling Stephen Hendry's record.

[5] The breakdown of prize money for the 2021 tournament is shown below:[2] The seedings were conducted on the basis of the one-year ranking list up to and including the 2021 Welsh Open.