The 2021 Rugby Europe Sevens Championship Series was the nineteenth edition of the continental championship for rugby sevens in Europe.

The series featured eight international sides and took place over two legs, the first at Lisbon in Portugal and the second at Moscow in Russia.

[1] it served as a qualifier to the 2022 World Rugby Sevens Challenger Series.

Spain were crowned champions having won both the Lisbon and Moscow legs.

[2] England, France, Ireland, and Wales did not field teams for this tournament due to the postponement of the 2020 Summer Olympics which took place from 26 July to 31 July 2021 - where Great Britain (encompassing England and Wales) and Ireland participated - as well as national COVID restrictions in France.