The 2021 season for Team Jumbo–Visma was the team's 38th season overall and the third season under the current name.

The team has been a UCI WorldTeam since 2005, when the tier was first established.

Ahead of the season, the team changed bicycle sponsor, as Canadian manufacturer Cervélo replaced Italian manufacturer Bianchi, which had been used by the team since 2014; the team also changed from rim brakes to disc brakes.

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