The 2021 Thüringen Ladies Tour (known as the Internationale LOTTO Thüringen Ladies Tour for sponsorship reasons) was the 32nd edition of the Thüringen Ladies Tour, a women's road cycling stage race being held between 25 and 30 May 2021 in the state of Thuringia in central Germany.

Given the cancellation of the 2020 edition, this edition was the first since its promotion after the 2019 season to a category 2.Pro event in the UCI Women's ProSeries.

Five teams chose not to field the maximum allowed squad of six riders; these teams were FDJ Nouvelle-Aquitaine Futuroscope, Maxx–Solar Lindig, Team Jumbo–Visma, Tibco–Silicon Valley Bank, and Trek–Segafredo, and they each entered five riders.

97 riders started the race, of which 83 finished.

[3] UCI Women's WorldTeams UCI Women's Continental Teams National Teams Elite Amateur Domestic Teams