The 2021 Tour Cycliste Féminin International de l'Ardèche was the 19th edition of the Tour Cycliste Féminin International de l'Ardèche road cycling stage race, which was held from 8 to 14 September 2021 in southeastern France.

[1] Five of the nine UCI Women's WorldTeams, 14 UCI Women's Continental Teams, and one Elite Domestic team made up the 20 teams that participated in the race.

[2] Ten teams entered a full squad of six riders, while eight teams entered only five riders.

Of the 108 riders to start the race, 79 finished.

[3] UCI Women's WorldTeams UCI Women's Continental Teams Elite Domestic Teams