The 2021 Tour of Belgium (known as the 2021 Baloise Belgium Tour for sponsorship purposes) was the 90th edition of the Tour of Belgium road cycling stage race, which took place from 9 to 13 June 2021.

The category 2.Pro event formed a part of the 2021 UCI Europe Tour and the 2021 UCI ProSeries.

[1] After being upgraded from a category 2.HC event after the 2019 season, the race was set to feature in the inaugural edition of the UCI ProSeries, but after the cancellation of the 2020 edition, this edition was its UCI ProSeries debut.

[4] UCI WorldTeam Israel Start-Up Nation were originally invited, but they withdrew due to a COVID-19 outbreak among their staff members.

Of the 146 riders who started the race, 137 finished.