The Men's 4 × 200 metres relay at the 2021 IAAF World Relays was held at Silesian Stadium on 2 May.

[1] Prior to the competition, the records were as follows:[1] (Nickel AshmeadeWarren WeirJermaine BrownYohan Blake) (Nickel AshmeadeWarren WeirJermaine BrownYohan Blake) (Javon FrancisJustin GatlinIsiah YoungEmmanuel Matadi) [1]