A significant number of games scheduled for 2021 are matches postponed from 2020 due to the COVID-19 pandemic.

The four teams were ranked based on their results in the group stage to determine the semi-final matchups.

The draw for the tournament took place on 9 January 2020, 19:00 CST (UTC−6), at the Estadio Akron, in Guadalajara, Mexico.

[16] Note: the table below has no impact on playoff qualification and is used solely for determining host of the MLS Cup, certain CCL spots, the Supporters' Shield trophy, seeding in the 2021 Canadian Championship, and 2022 MLS draft.

Renamed from United Soccer League (USL) after the 2018 season Bold = winner* = after extra time, ( ) = penalty shootout scoreSource: [1] Bold = winner* = after extra time, ( ) = penalty shootout scoreSource: Spring Season | National Independent Soccer Association On July 20, US Soccer finally announced that the tournament would be cancelled for 2021 and would resume in 2022.