The 2022–23 CAF Champions League group stage began on 10 February and ended on 1 April 2023.
The draw for the group stage was held on 12 December 2022, 12:00 GMT (14:00 local time, UTC+2), at the CAF headquarters in Cairo, Egypt.
The teams were seeded by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown next to every team).
The winners and runners-up of each group advanced to the quarter-finals of the knockout stage.
If tied on points, tiebreakers were applied in the following order (Regulations III.