[2] RS Berkane were the defending champions, but were eliminated in the playoff round by Union Monastirienne.

Notes: The draw for the qualifying rounds was held on 9 August 2022 at the CAF headquarters in Cairo, Egypt.

If the scores were still tied, extra time was not played, and a penalty shoot-out was used to determine the winner (Regulations III.

The draw for the group stage was held on 12 December 2022, 11:00 GMT (13:00 local time, UTC+2), at the CAF headquarters in Cairo, Egypt.

The mechanism of the draws for each round was as follows: The bracket was decided after the draw for the knockout stage (quarter-finals, semi-finals and final), which was held on 5 April 2023, 18:30 GMT (20:30 local time, UTC+2), at the CAF headquarters in Cairo, Egypt.