The 2022–23 season was the 103rd season in the history of CA Osasuna and their fourth consecutive season in the top flight.

The club participated in La Liga and the Copa del Rey, finishing as runners-up in the latter competition.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Source: Soccerway Source: La Liga The league fixtures were announced on 23 June 2022.