A total of 18 teams participated, 15 of which competed in the league campaign during the previous season, while the remaining three was promoted from the 2021–22 I liga.

As the 2022 FIFA World Cup started on 20 November, the league featured an extended pause during the season.

Raków Częstochowa clinched their 1st Ekstraklasa title on 7 May after Legia Warsaw lost 1-2 away against Pogoń Szczecin with three games remaining.

Wisła Kraków had been relegated to 2022–23 I liga for the first time since the 1993–94 season ending its twenty six-year stay in the top flight.

Bruk-Bet Termalica Nieciecza and Górnik Łęczna have been both relegated ending their one-year stay in the top flight.