Due to the ongoing situation resulting from the Russian invasion of Ukraine, Roberto De Zerbi left his role as Head Coach of Shakhtar in July.

[11] On 29 November, Shakhtar announced the signing of Giorgi Gocholeishvili to a five-year contract, effective from 1 January, from Saburtalo Tbilisi.

[14] On 31 January, Shakhtar announced the signing of Kevin Kelsy from Boston River on a contract until December 2027,[15] whilst Serhiy Kryvtsov left the club to join Inter Miami.

[18] On 12 March, Shakhtar terminated their sponsorship deal with Parimatch after the sports betting company was sanctioned by National Security and Defense Council of Ukraine.

[20] On 24 April, Shakhtar announced that they'd signed Denil Castillo to a five-year contract from Liga de Quito, commencing 1 July 2023.

[22] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.