The 2022–23 Holy Cross Crusaders men's basketball team represented the College of the Holy Cross in the 2022–23 NCAA Division I men's basketball season.

The Crusaders, led by fourth-year head coach Brett Nelson, played their home games at the Hart Center in Worcester, Massachusetts as members of the Patriot League.

9 seed in the Patriot League tournament, they lost to Loyola (MD) in the first round.

On March 10, 2023, the school fired head coach Brett Nelson.

In the Patriot League tournament, they were defeated by American in the first round.