2022–23 Iowa State Cyclones men's basketball team

They played their home games at Hilton Coliseum in Ames, Iowa as members of the Big 12 Conference.

They finished the season 19–14, 9–9 in Big 12 Play to have a two-way tie for 5th place.

They defeated Baylor in the quarterfinals of the Big 12 Tournament before losing to Kansas in the semifinals.

They received an at-large bid to the NCAA Tournament where they were eliminated in the first round by Pittsburgh.

[1] In Otzelberger's first season as head coach he claimed the best start to an Iowa State coaching career by winning his first 10 games,[2] ultimately winning his first 12 games before losing at home to No.