The 2022–23 LEN Euro Cup is the 31st edition of the second-tier European tournament for men's water polo clubs.

And it is the first year with the expanded format and presence of the LEN Challenger Cup.

The winners were A-Híd Vasas Plaket of Hungary, who defeated RN Savona of Italy on aggregate 23-15 in the final.

The top two ranked sides from each group advance to the eighth-finals.

[8] The twelve best teams from the 2nd qualification round of the Euro Cup and the four eliminated teams from the Champions League 3rd Qualification Round were drawn into 8 pairings, played on a home & away leg.