The 2022–23 LEN Women's Champions League is the 35th edition of the major competition for European women's water polo clubs.
It starts on 17 November 2022.
3 teams will progressed from each group.
The remaining 8 teams competed in the LEN Euro Cup for women.
CN Mataro (ESP), Olympic Nice (FRA), Vouliagmeni NC (GRE), Pacence (POR, host team), ZVL 1886 (NED) NC Glyfada (GRE, host team), ZV De Zaan (NED), CN Terrassa (ESP), Grand Nancy (FRA), Tigre Eger (HUN) Plebiscito Padova (ITA), UA Lille (FRA), Sirens ASC Malta (MLT), FTC-Telekom Budapest (HUN), CE Mediterrani Barcelona (ESP, host) Dunaujvarosi Foiskola (HUN), Spandau 04 Berlin (GER), SIS Roma (ITA), Ethnikos Piraeus (GRE), Mulhouse WP (FRA, host team) Ekipe Orizzonte (ITA), Plebiscito Padova (ITA) (Host), Dunaujvarosi Foiskola (HUN), ZVL 1886 (NED) Astralpool Sabadell (ESP), CN Mataro (ESP), Eger (HUN) (Host), FTC Telekom Budapest (HUN) UVSE (HUN) (Host), NC Glyfada (GRE), CE Mediterrani (ESP), Ethnikos Piraeus (GRE) Olympiacos Piraeus (GRE), SIS Roma (ITA) (Host), NC Vouliagmeni (GRE), ZV De Zaan (NED) Official source:[7] Official source: Official source: Official source: