The 2022–23 La Salle Explorers men's basketball team represented La Salle University during the 2022–23 NCAA Division I men's basketball season.

The Explorers, led by first-year head coach Fran Dunphy, played their home games at Tom Gola Arena in Philadelphia, Pennsylvania as members of the Atlantic 10 Conference.

12 seed in the A-10 tournament, they defeated Saint Joseph's in the first round before losing to Saint Louis in the second round.

On March 21, 2022, the school fired head coach Ashley Howard.

[1] On April 5, the school announced former Penn and Temple head coach, Fran Dunphy, would be the team's new head coach.