On 27 June 2022, Academica and Gaz Metan were relegated directly to Liga III, by the Romanian Football Federation, which denied a second tier licence for both clubs, due to important financial problems and unpaid debts to current and former players and managers.
[4] Due to Academica and Gaz Metan exclusion by the Romanian Football Federation, their places were occupied by Politehnica Timișoara and Unirea Constanța, best two ranked teams from the relegated five registered at the 2021–22 Liga II.
[3] Note: Flags indicate national team as has been defined under FIFA eligibility rules.
The teams will start the promotion play-offs with all the points accumulated in the regular season.
The teams started the relegation play-out with all the points accumulated in the regular season.