The 2022–23 Loyola Ramblers men's basketball team represented Loyola University Chicago during the 2022–23 NCAA Division I men's basketball season.

The Ramblers, led by second-year head coach Drew Valentine, played their home games at the Joseph J. Gentile Arena in Chicago, Illinois as first-year members of the Atlantic 10 Conference.

4 seed in the MVC tournament, they defeated Bradley, Northern Iowa, and Drake to win the MVC tournament for the second consecutive season.

As a result, they received the conference's automatic bid to the NCAA tournament as the No.

10 seed, where they lost in the first round to Ohio State.