On 25 May, Middlesbrough announced their pre-season plans with fixtures against Bishop Auckland (originally 25 June, later moved to 2 July), Morecambe and a training camp in Portugal.

[60] A day later, a trip to York City was added to the calendar.

[63] A sixth pre-season friendly was confirmed against Olympique de Marseille at home on July 22.

[64] A mid-season friendly during the 2022 FIFA World Cup winter break against Hibernian was announced.

[67] Middlesbrough finished 4th, in the regular season and were drawn against 5th place Coventry City Boro entered the FA Cup in the third round and were drawn at home to Brighton & Hove Albion.