The 2022–23 season was the 86th in the history of Nîmes Olympique and their second consecutive season in the second division.

The club participated in Ligue 2 and the Coupe de France, suffering relegation in the former.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Source: Soccerway Source: Ligue 2 The league fixtures were announced on 17 June 2022.