The 2022–23 NK Osijek season was the club's 109th season in existence and the 32nd consecutive season in the top flight of Croatian football.

This was the last season Osijek played their matches on Gradski Vrt Stadium.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Total Spending: €0 Total Income: €6,350,000 Net Income: €6,350,000 Last updated: 28 May 2023 Source: Soccerway Last updated: 28 May 2023.